Department of Pharmaceutical and Toxicological Chemistry

History of the department

The Department of Pharmaceutical and Toxicological Chemistry was organized in 1981. Since its opening until 1989, the department was headed by the Director of the ASMI Affiliate, E.T.Tegisbayev, Ph.D., associate professor. From 1989 to 2012 the department was headed by the laureate of the State Prize, Ph.D. T.A. Arystanova. Since 2012 the chair is headed by Ordabayeva S.K., Doctor of pharmaceutical sciences, professor.

Ordabaeva Saule Kutymovna – Doctor of pharm. sc., Professor, Head of the department

В the formation and development of the department was made by Rakhimova B.Kh., Merkusheva N.V., Mendibaev B.T., Kadyrova R.D., Myrzabaeva R.M., Zadorozhnaya E.V., Arystanova T.A., Shukirbekova A.B., Maralbaeva G.A., Makhova E. G. as well as Sopbekova A.O., Ordabayeva S.K. working to this day.
Tegisbaev E.T. made a significant contribution to the organization of the Chimkent filial of the ASMI, to the formation of the department of pharmaceutical and toxicological chemistry, the creation of a material and technical base, and the provision of human resources. For the Department of Pharmaceutical Chemistry alone, 9 candidates of pharmaceutical sciences were trained through targeted postgraduate studies at leading universities and research institutes of the USSR.
A huge contribution to the formation and development of the department was made by Arystanova T.A., Laureate of the State Prize of the Republic of Kazakhstan, Doctor of Pharmacy, Professor. She trained 2 doctors and 14 candidates of pharmaceutical sciences. Under her leadership, 1 international and 3 republican scientific and technical projects were completed, funded by the Ministry of Health of the Republic of Kazakhstan, the Ministry of Education and Science of the Republic of Kazakhstan, and the MIT of the Republic of Kazakhstan.
The goal of the department is to train highly qualified, competitive specialists with deep theoretical and practical training, professional competencies in the field of pharmaceutical and chemical-toxicological analysis.

Main tasks of the department:

• training of specialists with in-depth theoretical and practical training, professional knowledge, skills and abilities that meet the state educational standards of the specialty;
• maximum use and development of the methodological and personnel potential accumulated over previous years;
• development of creativity among students and teaching staff.

The department is a specialized department, where 2nd, 3rd, 4th, 5th year students of the Faculty of Pharmacy study in the following specialties: 6B10106 - “Pharmacy” and 6B07201 - “Pharmaceutical Production Technology” in Kazakh, English and Russian. Master's students of the first and second years of study are trained in the specialty 7M10142-"Pharmacy" in two directions: scientific-pedagogical and specialized, as well as for master's students SOP 7M10143 "Pharmaceutical Ecology" implemented with the First Moscow State Medical University named by I. M. Sechenov. Doctoral students are trained in EP 8D10140 “Pharmacy”.
The department, within the specialty “Pharmacy,” trains bachelors in the following trajectories: general pharmacist, pharmacy manager, clinical pharmacist; process engineer for maintenance of equipment and equipment, design engineer - designer with a specialty in “Pharmaceutical Production Technology”.

In accordance with EP 6M10106 “Pharmacy” (bachelor’s degree), the department teaches the following compulsory disciplines:

1. General methods of research and analysis of drugs, 150 hours (5 credits), 3rd year, 5th semester, teaching in Kazakh, English, Russian.
2. Analysis of medicines of natural origin, 120 hours (4 credits), 3rd year, 6th semester, teaching in Kazakh, English, Russian.
3. Pharmaceutical chemistry-1,2, 150 hours each (5+5 credits), 4th year, 7,8 semesters, teaching in Kazakh, English, Russian.
4. Toxicological chemistry-1,2, 120 hours each (4+4 credits), 5th year, 9th, 10th semesters, teaching in Kazakh and Russian.

The elective components (elective disciplines) include the following:

1. Standardization of medicines and metrology 180 hours (6 credits), 5th year, 9th semester, teaching in Kazakh, English, Russian.
2. Bioanalytical chemistry and toxicology, 150 hours (5 credits), 4th year, 7th semester, teaching in Kazakh and Russian.

Industrial practice is carried out: “Quality control and standardization of medicines” 60 hours (2 credits); “Toxicological chemistry”, 60 hours (21 credits).
In accordance with EP 6B07201 - “Pharmaceutical Production Technology”, the department teaches the specialized discipline “General Chemical Technology”, 150 hours (5 credits), 3rd year, 6th semester, teaching in Kazakh, Russian and English.

The elective components (elective disciplines) in this specialty include the following:

1. Chemistry and technology of synthetic drugs, 120 hours (4 credits), 4th year, teaching in Kazakh, Russian;
2. 3. Methods and equipment of pharmaceutical analysis, 120 hours (4 credits), 4th year, teaching in Kazakh, Russian.

At the master's level in EP 7M10142 "Pharmacy" the following disciplines are taught: "Instrumental methods of analysis", "Structural analysis of drugs", "Methodology for performing dissertation works", "State of production and quality control of drugs", "GLP rules for the creation of new drugs" " When implementing the EP 7M10143 “Pharmaceutical Ecology”, classes are conducted in the following disciplines: “Physico-chemical methods of analysis”, “Pharmaceutical chemistry”, “Toxicology” and “Bioanalytical chemistry and toxicology”. To date, the department has trained 16 masters of pharmacy, 2 - preparation stage.
According to EP 8D10140 “Pharmacy”, classes are conducted on university components and elective components: “Methodology of scientific research in pharmacy”, “Physico-chemical methods for testing quality indicators”, “Methodology for conducting chemical-toxicological studies”.
The employees of the department are carrying out targeted work in the research direction of the department “Search, creation and implementation of medicinal products based on domestic plant raw materials.”

The priority scientific directions of the department are:

1. Targeted search and production of new modified substances based on biologically active compounds of the components of licorice root and wormwood.
2. Creation and standardization of effective and safe medicines based on domestic plant raw materials.
3. Development and improvement of methods for analyzing drugs using physicochemical methods.
4. Chemical-toxicological analysis of potent and toxic substances.

Employees of the department are carrying out scientific and technical projects: “Development of effective and safe medicines based on domestic plant raw materials.” Implementation period: 2018-2024.
The employees of the department are the authors of the state compulsory education standards (SCES) of the Republic of Kazakhstan in the following specialties: 0902 – “Management in the social sphere (pharmacy)” (SCES RK, 1998); 0409 – “Pharmaceutical production technology” (State Standard of Education of the Republic of Kazakhstan, 1998); 051103 – “Pharmacy” (“Bachelor’s degree” of the State Educational Standard of Education of the Republic of Kazakhstan, 2006); 7.09.111 - “Pharmacy” (“Master’s degree” of the State Educational Standard of Education of the Republic of Kazakhstan, 2009); 5B110300 “Pharmacy” (“Bachelor’s” State Educational Standard of the Republic of Kazakhstan, 2017 with additions and changes).
Employees of the department are co-authors of 16 standard training programs in the disciplines of the specialties “Management in the social sphere (pharmacy)”, “Pharmacy”, “Pharmaceutical production technology”.
Employees of the department have developed: preliminary patents of the Republic of Kazakhstan - 24, patents for utility models - 4, Certificates of Authorship - more than 30, registration certificates for medicinal products - 5, temporary pharmacopoeial articles - 5, Standard operating procedures included in the register of forensic examination methods at the Forensic Center examinations of the Ministry of Justice of the Republic of Kazakhstan - 2, more than 650 scientific works, including in international publications, materials of scientific forums - about 200 (USA, Russia, Austria, Italy, Finland, Thailand, Czech Republic, Bulgaria, Ukraine, etc.), in republican - more than 400, 5 monographs, 9 reviews, 16 textbooks, 2 laboratory workshops have been published.

The department carries out certain work on international cooperation within the framework of the educational process and research work.
Great support in the development of the department was provided by the Faculty of Pharmacy of the Moscow State Medical University by I. M. Sechenov, headed by Academician of the Russian Academy of Medical Sciences A.P. Arzamastsev, who organized visiting lectures, seminars, and consultations with professors of this university. Under the leadership of Arzamastsev A.P. 3 candidates of pharmaceutical sciences were prepared for the department.
Joint educational programs have been developed with foreign partner universities: Republican unitary enterprise for production practice “Quality control and standardization of medicines”, approved by the Academic Councils of SKMA and the First Moscow State Medical University named by I. M. Sechenov (2014); a similar RUP, approved by the Academic Councils of SKMA and BSMU (2016, 2018);
At the master's level, SOP 7M10143 “Pharmaceutical Ecology” was developed, approved by the Academic Councils of SKMA and the First Moscow State Medical University named by I. M. Sechenov (2022) and included in the register of EP of the Unified Educational Platform of the Ministry of Education and Science of the Republic of Kazakhstan.
A joint methodological manual “Quality control and standardization of medicines” was published, approved by the Academic Council of SKMA and the First Moscow State Medical University (2014), supplemented and republished in 2018 (Moscow: GEOTAR-Media).

Since 2013, as part of the implementation of the program of the Ministry of Education and Science of the Republic of Kazakhstan to attract foreign teachers to the educational process “Academic Mobility,” leading scientists from partner universities have been visiting: professor Ramenskaya G.V., associate professors Pechennikov V.M., Vlasov A. M., Smirnova V.V. (I MSMU, Moscow, Russian Federation); Associate Professor Bevz N.Yu. (NFAU, Kharkov, Ukraine); Professor Khaliullin F.A. (BSMU, Ufa, Russia); Professor J. Jampilek (University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic); Ass. Professor B. Wielgomas (SMU, Gdansk, Polish Republic); Professor Shukirbekova A.B. (MU “Astana”, Republic of Kazakhstan), etc.
External visit of Professor S.K. Ordabayeva carried out on the bases of BSMU and State Medical University for the purpose of conducting master classes, practical classes and sharing experience in research work.
Since 2015, the department annually, on the basis of the educational and scientific laboratory, accepts students from the First Moscow State University named after. Sechenov and the Bashkir State Medical University for practical training “Quality control and standardization of medicines”.
Dual education is provided for 5th year students by combining theoretical training in the discipline “Standardization of Medicines and Metrology” at the Department of Pharmaceutical and Toxicological Chemistry with practical training at the production base of Khimpharm JSC - Santo Member of Polpharma Group.”
A student scientific circle “Pharmacy of the Future” has been organized from among 3-5 year students who actively participate in annual scientific and practical conferences, forums and symposiums of young scientists and students. More than 20 students are winners of annual scientific and practical conferences of young scientists and students.

Today, the department employs 11 teachers, including 1 doctor, 6 candidates of pharmaceutical sciences, 3 doctoral students, 3 masters of pharmacy, 2 master’s students:

1. Ordabaeva Saule Kutymovna – Doctor of pharm. sc., Professor, Head of the department;
2. Sopbekova Anarkul Onlabekovna – cand. of pharm. sc., acting. professor;
3. Asilbekova Akmaral Dzhienbekovna - cand. of tech. sc., acting professor;
4. Serikbaeva Aigul Dzhumadullaevna - cand. of pharm. sc., acting associate professor;
5. Tursubekova Bayan Izteleuovna - cand. of pharm. sc., acting associate professor;
6. Kadeeva Mansia Sadilovna - cand. of pharm. sc., associate professor;
7. Onerbay Bek Akylbekovich - cand. of pharm. sc., professor of SKMA;
8. Karakulova Aizhan Shirynbekovna - Master of Pharmacy, senior teacher;
9. Nurkhanova Gulnara Zhaksylykovna - Master of Pharmacy, teacher;
10. Altynbek Dana Turgankulovna - Master of Pharmacy, teacher;
11. Dzhanaralieva Kakha Saidovna - senior teacher;
12. Bidaybek Ramazan Nurgazyuly - doctoral student of the third year of study;
13. Karabaeva Ainur Nysanbekovna - doctoral student of the first year of study;
14. Musabekov Zhankeldy Tuimebekovich - doctoral student of the first year of study;
15. Nursultankyzy Moldir - master's student of the second year of study;
16. Abdukarimova Kamola - master's student of the first year of study;
20. Zhorabekova Raikhan Almakhanovna - senior laboratory assistant;
21. Rysbekova Meiramkul Abdrakhmanovna - laboratory assistant;
22. Mamirova Ulbanu - laboratory assistant;

The department is located at the address: Shymkent, sq. Al-Farabi-1.
E-mail: phamchim@mail.ru
Phone 408-222 (ext. 226)